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Phentermine: Usage, Dosage, Side Effects, Drug Interactions

Phentermine is an appetite suppressant drug that is commonly used for weight loss. It’s prescribed to people who are overweight and those who are considered obese, as it helps to reduce their calorie intake. Its active ingredient is Phentermine Hydrochloride, a stimulant that works by increasing the levels of certain hormones in the body, such as adrenaline and noradrenaline.

However, like any other medication, Phentermine has potential side effects and risks. It may interact with other drugs, too. In this guide post, we will discuss Phentermine usage, dosage, side effects, and drug interactions. So read on to find out more about this medication and its potential risks.

What is Phentermine?

Phentermine is a medication used for short-term weight loss. It is generally prescribed for people who are overweight or obese and have been facing failure to lose weight by diet and exercise alone. The drug has the ability to suppress appetite and increase energy levels, making it easier for people to eat less and/or exercise more.

It is a sympathomimetic amine, which means it stimulates the sympathetic nervous system. Phentermine is structurally similar to amphetamines and acts as a central nervous system stimulant. It increases blood pressure and heart rate, which helps to decrease appetite. Phentermine is FDA-approved for short-term use, and it is typically prescribed for people who are obese or overweight with other health risks.

How to take Phentermine

Phentermine is available in both tablet and capsule form. You can take it once a day, either with or without food. The typical adult dose is 15-37.5 mg per day. Phentermine should not be used for longer than 12 weeks at a time, as it can be habit-forming.

When taking Phentermine, it is important to follow the instructions of your prescribing physician carefully. You should take Phentermine on an empty stomach, half an hour before your first meal of the day or 1-2 hours after breakfast. Phentermine should not be taken late in the day as it may cause insomnia.

Phentermine Side Effects

Common side effects of Phentermine include:

  • Dry mouth
  • Increased heart rate
  • Restlessness
  • Insomnia
  • Headache
  • Anxiety
  • Dizziness

Rare side effects of Phentermine include

  • Hyperactivity
  • Confusion
  • Tremor
  • Diarrhea
  • Constipation
  • Stomach pain
  • High blood pressure
  • Increased heart rate

In the event of such side effects, please discontinue use and contact your doctor immediately.

Who should not consume the drug?

  • Phentermine is not recommended for use in children under the age of 16 years old.
  • It is prohibited to consume the drug if you are pregnant or breastfeeding, or if you have heart disease, high blood pressure, arteriosclerosis (hardening of the arteries), hyperthyroidism, or a history of drug abuse.
  • If you are taking a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).

Phentermine Drug Interactions

Being a Schedule IV drug, the drug has a high potential for abuse. Therefore, it is only available by prescription. It is also advisable not to take it with other appetite suppressants, MAO inhibitors, or tricyclic antidepressants.

Taking Phentermine with these drugs can cause serious side effects, including stroke, heart attack, and death. Phentermine should also not be taken with alcohol as it can increase the risk of developing pneumonia.

Can You Buy Phentermine Online?

Phentermine is a controlled substance and must be prescribed by a licensed healthcare provider. However, it is possible to buy Phentermine online from websites that do not require a prescription. These websites are often referred to as “grey market” pharmacies. While buying Phentermine online without a prescription is legal, it can be risky.

The medication may be counterfeit, sub-standard, or adulterated. In addition, there is no way to verify the authenticity of the website or the safety of the transaction. For these reasons, it is generally recommended that people only purchase Phentermine from a licensed healthcare provider.

Can Phentermine cause depression?

Phentermine is a weight-loss medication that has been shown to be effective in short-term use. However, there is some concern that it may be associated with depression. Amidst its unknown mechanism of action, the drug is thought that Phentermine may affect certain chemicals in the brain that are linked to depression.

In addition, people who are struggling with their weight may be more likely to experience depression, so it is possible that Phentermine is not the direct cause of depression but rather a contributing factor.

If you are taking Phentermine and notice any symptoms of depression, difficulty concentrating, changes in appetite or sleep patterns, or thoughts of suicide, be sure to talk to your doctor.


Phentermine is a prescription medication used to treat obesity and weight-related conditions. While it can be effective, it’s important to understand its usage, dosage, side effects, and drug interactions before taking the drug. People should always consult with their healthcare provider for personalized medical advice about taking or stopping any prescription medications.

By understanding all information related to phentermine use, people can ensure that they are making an informed decision when considering this option for managing their weight-related condition.

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