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Percocet: Usage, Dosage, Side Effects, Drug Interactions

Percocet is a prescription drug that is highly useful for treating moderate to severe pain. It is a combination of acetaminophen and oxycodone, an opioid. When taken as directed by your doctor, it can be an effective way to manage your pain.

However, there are potential risks associated with Percocet that you should be aware of and consider before taking the medication. In this guide post, we will discuss the usage, dosage, side effects, and drug interactions of Percocet so you can better understand why certain precautions need to be taken with this medication.

What is Percocet?

Percocet is a prescription medication that contains a combination of acetaminophen and oxycodone. It is highly useful for relieving moderate to severe pain. Oxycodone is an opioid pain medication, and acetaminophen is a non-opioid pain reliever and fever reducer.

Percocet is a controlled substance, which means it is subject to special regulations because it has the potential for abuse and dependence. It should only be taken as directed by a healthcare provider and should not be shared with others.

The exact mechanism of action of Percocet is not known, but it is thought to work by inhibiting the reuptake of norepinephrine and serotonin in the brain, which leads to increased levels of these neurotransmitters in the brain.

This provides relief from pain by reducing the perception of pain.
The extended-release form of this medicine is for the around-the-clock treatment of pain. This form of Percocet is not for use on an as-needed basis for pain.

Dosage and Administration

Percocet is available in tablet form for oral administration. The recommended dose for adults is 1-2 tabs every 4-6 hours as needed. The maximum daily dose should not exceed eight tablets.

It should be taken with food or milk to reduce the risk of stomach upset. Moreover, as the drug can be habit-forming, you should only use the drug if prescribed by your doctor. Lastly, you should store it at room temperature, away from light and moisture.

What are the side effects of Percocet?

Percocet may cause serious side effects including :

  • Liver damage
  • Kidney damage
  • Respiratory depression

In the event of such side effects, call your doctor immediately. Other common side effects of Percocet include:

  • Constipation
  • Nausea
  • Vomiting
  • Drowsiness
  • Lightheadedness
  • Dizziness

Percocet can also cause mood swings and irritability. The drug’s effects on the brain can lead to changes in mood and behavior. Some people may become more withdrawn, while others may become more aggressive or angry. These mood changes can be unpredictable and may come and go without warning.

Drug interactions with Percocet

Percocet may interact with other medications that you are taking. Keep your doctor in the loop about any medications you are taking, including vitamins and herbs. It is also advisable not to pause the medication without first talking to your doctor.

The following medications may interact with Percocet:

  • Antidepressants
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Lithium
  • Trazodone
  • St. John’s wort

Precautions when taking Percocet

Before you buy Percocet online, acknowledge the potential risks and side effects involved. Here are some precautions to take when taking Percocet:

  • Percocet can be habit-forming. If you have a history of drug abuse or addiction, be sure to discuss this with your doctor before taking Percocet.
  • Percocet can interact with other medications, so be sure to tell your doctor about all the medications you are taking, including over-the-counter drugs.
  • Percocet can cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how Percocet will affect you.
  • Drinking alcohol while taking Percocet can increase the risk of serious side effects. Avoid drinking alcohol while taking Percocet.
  • Be sure to follow your doctor’s instructions when taking Percocet. Moreover, do not overdose on the medication.

Can you buy Percocet Online?

Yes, you can buy Percocet online but acknowledge the risks involved in doing so. Many online pharmacies claim to sell Percocet, but many of them are not legitimate. It is important to only purchase Percocet from a reputable source.

Additionally, Percocet is a controlled substance that comes with certain legal ramifications for persons buying it online. Finally, because Percocet is a potent pain medication, it is important to use it only as directed by a doctor or pharmacist.


Percocet is an effective pain reliever, but with the guidance of a doctor, it can easily become a drug abuse amongst users. It can cause serious side effects if taken in large doses or combined with other medications without being aware of potential drug interactions.

Therefore, it is important to take this medication as directed by your physician and be sure to keep track of any changes in your symptoms. By following these guidelines, you can ensure that you are using Percocet safely and effectively for optimal relief from pain.

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